Data concerning the safety and possible efficacy of rFVIIa in patients with polytrauma and TBI will need to be deduced from studies in hemodynamically stable patients with TBI.
- How the enzyme component of CDT is translocated through the pore, is deduced from studies with iota toxin and C2 toxin.
The role of Sema3A in maturation and/or differentiation of the distal lung epithelium during development was deduced from studies on Sema3A-null mice.
Comparisons between the genomes of apple and pear, which belong to the subfamily Maloideae, indicate a very high level of synteny, and no major chromosomal rearrangements can be deduced from studies of common markers mapped in these genera [ 16, 17].
For intraperitoneal (ip) injections, drugs were dissolved in 0.9% saline; the doses used, that is, 0.1 mg/kg SCH-23390 and 5 mg/kg SKF-38393, were deduced from studies on mechanisms of emotional learning in rats (Greba and Kokkinidis 2000; O'Tuathaigh and Moran 2002).
One possible mechanistic explanation for these paradoxical effects can be deduced from studies showing that POPs such as dioxin lead to a decrease in liver gluconeogenesis in several cellular and animal models mainly through the repression of phosphenolpyruvate carboxykinase (Viluksela et al. 1999).
The applied dose of m-CPP was within the range shown to exert, after intrastriatal infusion, similar effects as intrastriatal SKF-38393 on oral activity responses in rats (Plech et al. 1995); the doses of SCH-23390 and SKF-38393 were deduced from studies on mechanisms of working memory and attentional performance in the rat prefrontal cortex (Seamans et al. 1998; Granon et al. 2000).
Rather, systems this size seem to obey a unique set of rules that cannot be deduced from studying their individual components.
By definition [ 4, 5], trait-mediated indirect effects emerge only in the context of population or community interactions and cannot easily be deduced from study of isolated, focal hosts.
Solute solvent interactions of sodium acetate in water and aqueous methyl acetate (20% by weight) have been deduced from conductance studies.
