Sentence examples for been convincingly shown by from inspiring English sources

Estrogen protection from angiotensin II induced and other models of cardiac hypertrophy and fibrosis has been convincingly shown by several groups (43– 43).

Fibrillization of Aβ has been convincingly shown by in vitro studies to consist of a two-step process that requires first the nucleation of a seed, before polymerization into amyloid fibrils [ 14, 38].

Recently, it has been convincingly shown by the means of sophisticated systematic knockout experiments on 41 candidate genes in the critical 5q− region that the gene for a ribosomal subunit protein, RPS41, seems to be a relevant gene in patients with 5q− syndrome on the basis of haploinsufficiency [ 22].

This was convincingly shown by several studies which re-populated cells in de-cellularized lungs of different matrix compositions [94 96].

The involvement of calcitonin gene-related peptide (CGRP) in migraine pathophysiological mechanisms is convincingly shown by the facts that CGRP can induce migraine [1] and that two CGRP antagonists, olcegepant [2] and telcagepant [3, 4], are effective in the treatment of migraine attacks.

That thrombin-dependent APC generation mediates protective effects in sepsis models was convincingly shown by direct infusion of APC into baboons challenged with Escherichia coli [ 31].

These hypotheses have rarely been rigorously tested, because of a lack of sufficient wild samples [e.g. for cattle, [ 6]] and/or phylogeographic structure [e.g. for dogs, [ 10]] although a multiregional origin has been convincingly shown for pigs by comparing DNA from domesticated pigs and wild boars from various areas around the world [ 7].

The exact mechanisms underlying the detrimental effects of aneuploidy remain unclear, but it has been convincingly shown that they are caused by the expression of the extra genes on the supernumerary chromosome [ 3].

It has been convincingly shown, and generally accepted, that by considering DNA sequence conservation between mouse and human, the over-predictive nature of TFBS modeling can be significantly remedied.

To date, only variation in FTO has been convincingly shown to impact type 2 diabetes by an intermediate effect on body mass index (BMI) and adiposity [ 69].

Such events where ER fission is followed by fusion has been convincingly shown in starfish eggs following fertilization-induced ER fission [20].