An award of award of £777,958 is set to allow the purchase of the historic market hall in Newtown, Powys, so it can be converted to a venue hosting two social enterprises as well as offering short-term leases to small businesses.
In the host, inactive PLG is converted to active plasmin by host-expressed tissue-type PLG activator (tPA) and urokinase (uPA).
T1106 is converted to a triphosphate form by host enzymes and likely inhibits the replicase activity of FMDV 3Dpol, although the exact mechanism of FMDV inhibition by T1106 is unknown.
NRTIs are pro-drugs that must be converted to their triphosphate forms by host cellular enzymes.[ 38] The kinetics of NRTI phosphorylation, which varies greatly between different cell types, complicates the in vitro assessment of how potent an NRTI will be in vivo.
Either (i) the associates' character matrix is converted to a character matrix of the hosts, the latter being used to compute host distances, or (ii) distances between the associates are computed from the associates' character matrix and the resultant distance matrix is converted to a distance matrix of the hosts.
Two categories have been identified, those capable of causing DNA damage and mutations directly (genotoxic, or direct-acting, carcinogens) and those that require prior metabolic activation by cells of the host to be converted to mutagens (epigenic, or indirect-acting, carcinogens).
Using E. coli as a whole-cell biocatalytic host, monacolin J was converted to simvastatin using a LovD expression strain and feeding of DMB-SNAC.
Before replication, the viral genome is converted to DNA and then integrated into the host genome.
We have identified a transfer of metabolites from host to endosymbiont, showing that Drosophila Lpp-lipids are used by Spiroplasma for proliferation and more specifically provide evidence indicating that host-derived DAG is converted to cardiolipin by Spiroplasma.
