Quantitative structure activity relationship (QSAR) models were constructed for predicting the inhibition of furin-dependent processing of anthrax protective antigen of substituted guanidinylated aryl 2,5-dideoxystreptamines.
In several other studies [ 10- 12], regression models instead of classifiers were constructed for predicting siRNA efficacy.
A separate model was constructed for predicting the risks of breast, colon and prostate cancer in the first-degree relatives.
As no alignment data were available for MSH6 in the Align-GVGD website, a protein alignment was constructed for predicting the functional effect of MSH6 missense variants from MSH6 homologues in eight species (human, chimpanzee, dog, cow, pig, mouse, chicken, frog and zebrafish).
By using the available data from experimental studies, classifiers can be constructed for predicting either the free energy change (ΔΔ G) of protein stability upon mutations or the direction of the change (increased stability if ΔΔ G > 0, or decreased stability if ΔΔ G < 0).
ROC curves were constructed for Predict models with (v3) and without (v2) Kinputnput.
Due to the requirements for probe specificity, probes could not be constructed for all predicted CGIs.
In-house bioinformatics pipelines were constructed for profiling and predicting novel miRNAs from sequencing data [ 33].
Let n be the number of clusters in C*, and m be the number of complexes in M *, then a n × m confusion matrix Z is constructed for comparison between predicted clusters and benchmark complexes.
Based on the FEA results, the Kriging metamodels are constructed for the two columns to predict the crashworthiness criteria of specific energy absorption (SEA) and peak crushing force (PCF) under oblique impact loading, which are set as design objectives in the following multiobjective optimization design (MOD) process.
A life table was constructed for each cohort based on predicted age specific incidence of breast cancer, breast cancer specific mortality, and mortality from other causes (web appendix).
