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For these reasons, bacterial phylogenetics has been constrained to studies of specific genes or to cultured organisms, which represent a small and biased portion of the bacterial tree of life.
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As a consequence, the researcher is constrained to study each one of the coexpressed gene sets individually, losing much of the potential that the technologies for obtaining gene expression arrays offer.
To date, the study of nonadherence has been constrained to clinical studies.
For this reason, most synthetic peptide studies have been constrained to relatively short (no longer than the low 40s) polyQ repeat lengths and truncated C-termini.
Studies have thus been constrained to either include few samples or only describe the dominant members of the communities.
Where ARH is constrained to case control studies the approach to establish the probability distribution within the samples allows extension of the analyses to more than two conditions.
Invariance testing proceeded by comparing the chi-square value of this model to a model where item thresholds were constrained to equality across studies (scalar invariance).
Nissen and Wolski were constrained to meta-analyze studies that mostly had <5 events in all, several indeed with 0 events.
The results presented in Figure 1 are constrained to the larger study, where the most significant ALT elevations were observed (patient demographics in Supplementary Table S4. The primary endpoints analyzed were biomarkers (ALT, AST, and serum bilirubin) measured from serial serum samples.
To avoid edge effects between different tissue types, group comparisons were constrained to voxels in the study-specific template with a tissue probability >0.25.
This simplistic hypothesis, the direct relation between snow depth and the aphid distribution, was rapidly entrenched in polar science, becoming a modern axiom in Arctic ecology, even though the field study was constrained to six D. octopetala patches in a 2.7 by 3.5 m south facing plot in a single location within the settlement of Ny-Ålesund [ 6].
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