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In binary networks there has been considerable study of synchronous as opposed to asynchronous updates, where in the former case the gene activity levels at time t are used to update all of the activity levels at time t+1.
While there has been considerable study of particular comorbid combinations, including study of costs [ 18, 19] and OOPE [ 20, 21], these are targeted studies and there has been little if any work which looks at the relative impacts across a range of comorbidities.
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There has also been considerable study and modeling of rockfalls as an engineering hazard to infrastructure (roads, railways and buildings in mountain areas) has also been done, including estimates of rockfall magnitude and frequency from tree-ring records.
One of the primary findings of this systematic literature review was considerable study variability, both in the combination of and ways in which CCM elements were implemented.
During the 20th century there has been considerable progress in the study of animal cognition, based on essential ideas that were developed earlier.
Given the impact of BAG-1 overexpression on multiple growth control pathways, there has been considerable interest in studying the significance of BAG-1 in human cancer.
Given its high temperature tolerance, there has been considerable interest in studying the mechanisms of thermoadaptation in A. pompejana, and in establishing sequence-resources for this organism [ 5].
Perhaps unsurprisingly, there has been considerable variation between studies in their detection of known Wnt targets and in their identification of new targets.
Thus, there has been considerable interest in the binding studies of small molecules with DNA.
In order to resolve some of the controversies surrounding the origin and composition of granulites, it is necessary that considerable studies of these rocks be conducted in the future.
Overall, there were no consistent adverse effects of iron supplementation; however, not all studies monitored for adverse effects of iron supplementation and there was considerable between study variability in the types of adverse effects monitored / reported.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com