Sentence examples for been conserved in active from inspiring English sources

This single Abpa- Abpbg gene pair appears to have been conserved in active form in most mammalian lineages (e.g., cat and dog), but was silenced by pseudogenization in primates (represented in this study by bushbaby, chimpanzee and human).

At least one Abpa and Abpbg gene was present in the last common ancestor of eutherians and metatherians, approximately 180 MYA, and this single Abpa- Abpbg gene pair has been conserved in active form in most mammalian lineages, but was silenced by pseudogenization in primates.

The active site zinc ion (Zn2+) has been conserved in all classes of carbonic anhydrases [ 1].

Nine water molecules are conserved in the active site and form an intricate hydrogen-bonding network with the co-factor and the surrounding amino acid residues.

These two aspartic acid residues are conserved in the active VMA homing endonucleases (S. cerevisiae, S. cariocanus and Z. baillii).

In this study, the residues in the lyase domain of VenL that are conserved in the active site of OspF proteins were mutated to evaluate their importance for catalysis.

The nucleophilic cysteine residue and the adjacent histidine residue, which are conserved in all active dual-specificity phosphatases, are replaced by serine and phenylalanine residues respectively in MK-STYX.

The SID domain is conserved in all known active and inactive members of the myotubularin family [25], [26].

This asparagine residue is conserved in most other active E2s, whereas in Ube2W the equivalent residue is histidine.

Furthermore, miRNAs are conserved in evolution but become active in polyploidisation [ 25, 13].

These residues are conserved in PI3Kα, and the active inhibitors in general appear capable of matching those requirements.