Sentence examples for been closely implicated in from inspiring English sources

As an assisted witness, Ms. Lagarde has not been placed under formal investigation but is considered to have been closely implicated in the case, which involves a half-billion-dollar state payout to Bernard Tapie, a businessman and politician who once served time in prison for his involvement in the fixing of soccer matches.

The SIRTs have been closely implicated in both protection against and generation of cardiac disease [ 65- 68] (Table 2).

Epithelial-mesenchymal transition (EMT) is closely implicated in the pathogenesis of idiopathic pulmonary fibrosis.

Abnormal expression of γ-Glutamyltranspeptidase (GGT) in living organisms is closely implicated in the development of several human tumors.

Although we observed that high expression of GNA13 in HCC was closely implicated in tumor progression, further investigation is needed to fully elucidate the precise mechanisms of GNA13 involved in the metastasis and progression of HCC.

As an anti-apoptotic protein, API5 may be closely implicated in the regulation of apoptosis and is highlighted as a potential drug target in cancer.

These neurons are closely implicated in descending bulbospinal inhibitory control, and such loss may upset the natural endogenous pain-suppressing mechanisms.

Moreover, accumulating evidence has suggested that reactive oxygen species (ROS) are closely implicated in modulating autophagic responses via complex interactions with other autophagy-related factors.

Retrotransposons are known to be closely implicated in genome reshaping [ 1], but Miniature Inverted-repeat Transposable Elements (MITEs) could also be implicated, since they have very high copy numbers and display recurrent bursts of transposition [ 2, 3].

As shown in Table 2, about half of these genes encode proteins likely to be closely implicated in gene regulation or signal transduction, although their targets are mostly unknown.

From this, it immediately follows that aaRS side chains forming interior of the synthetic and editing sites are closely implicated in the selection of 2′- or 3′-OH variants.