Sentence examples for been clearly established although from inspiring English sources

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The factors that drive inflammation in COPD after smoking cessation have not been clearly established although autoimmunity, embedded particles/heavy metals from smoking and chronic bacterial infection have all been proposed to have a role [11].

The pathogenesis of FCDs has not yet been clearly established, although a number of histopathological patterns and molecular findings suggest that they may be due to abnormal neuronal and glial proliferation and migration processes.

The pathogenesis of such involvement has not yet been clearly established, although knowledge of the physiopathology of leptospirotic pneumonitis suggests the participation of immunological mechanisms in the development of pulmonary forms of the disease [ 9, 10].

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A physiological role of MOG in the CNS has not been clearly established thus far, although several functions were proposed.

The precise haemodynamic effects of citrate in ALF have not been clearly established [ 21], although it appeared to be safe in one study of patients with liver failure (mostly ALF) supported by a molecular adsorbent recirculating system [ 22].

The role of VDR and 1,25(on)2D3 on TRPV6 expression has been clearly established in mice (22, 24) although some recent work has challenged how critical TRPV6 is to overall calcium absorption (17).

In a 35-page opinion, the judges state that "Although it has been clearly established for decades that torture of an American citizen violates the Constitution, and we assume without deciding that Padilla's alleged treatment rose to the level of torture, that such treatment was torture was not clearly established in 2001-03".

Although it has been clearly established that understanding others' social intentions calls on brain regions which are partly associated with the mentalizing network, the contribution of motor resonance by means of the activation of the action observation/execution matching network (i.e. mirror system) is still a controversial issue.

Although hyperglycemia has been clearly established by the DCCT/EDIC [ 5] and other subsequent studies to be a key mediator of CVD risk in T1D [ 4, 23, 25], hyperglycemia explained only a modest fraction of this overall risk and the mechanisms underlying excessive CVD mortality had not been defined [ 6].

Most antipsychotics are thought to have an effect on D2 and D3 receptors, although their D3, versus D2 binding has not been clearly established in vivo in humans.

Although the tumor suppressing activity of p53 has been clearly established, less attention was given to its possible involvement in the processes of cell differentiation and development.

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