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However, since a favourable effect of the treatment may not have been clearly determined at the time of TES participation (with results from the preceding RCT and/or indeterminate prior studies not available), this raises legitimate ethical issues about the appropriateness of exposing patients to potentially ineffective or only partially effective treatments for additional periods of time.
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Entering enemy terrain, the President was clearly determined to make it his own — at least for one night.
That was the last time that happened, in 2010 at the Australian Open, and Sharapova was clearly determined not to have a repeat.
Chemicals with a photoallergenic potential also showed phototoxic effects at higher concentration ranges that could be clearly determined in our in vitro assay.
The Russian had lost her last two Grand Slam finals at Wimbledon and the Australian Open but was clearly determined not to slip up again.
In the cellar at Haut de la Garenne this week, the searching officers were clearly determined that a blind eye would be turned no longer.
Mr Straw is clearly determined not to be outflanked by the Tories on law and order, even at the risk of alienating sections of his party.
Entering enemy terrain, the President was clearly determined to make it his own at least for one night.
Ms. Conner is clearly determined.
They are clearly determined not to simper so much.
He was clearly determined to get it right this time.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com