Polycomb mutations were classically shown to act in embryogenesis primarily by maintaining Hox gene silencing.
If one were to apply this measure to an analysis of individual plasticity within populations, an interesting paradox may emerge where individual birds that are classically shown as being plastic in response to daily average temperatures would actually maintain the same relationship between their timing of breeding and the heat accumulation.
In addition to combat with predators using horns, Triceratops are classically shown engaging each other in combat with horns locked.
Thin collimated spiral CT completed with high spatial frequency reconstruction (HRCT) has a high diagnostic accuracy for PLCH when a combination of nodules and cysts is classically shown [15, 16, 17].
To support this fact, it has been described that membrane-bound ectopeptidases can affect, in solid tumors, cellular events classically shown to be influenced by matrix metalloproteinases (MMPs) and other secreted proteases [ 27].
Although only a few dozen genes have been shown to be classically imprinted in humans, it is possible that subtle imprinting effects could be more widespread (Schalkwyk et al., 2010); for nonhuman mammals, recent research has extended the list of imprinted genes from about 100 to more than 1,000 (Gregg, Zhang, Butler, Haig, & Dulac, 2010; Gregg, Zhang, Weissbourd, et al., 2010).
In this study, we have shown that macrophages recovered from F. hepatica-infected mice are alternatively activated, however, macrophages from mice co-infected with T. gondii were shown to be classically activated, similar to those found in mice infected with T. gondii alone.
RFX6 is classically associated with regulating insulin expression and has recently been shown to be essential for islet cell differentiation in the murine pancreas [ 52, 53].
Pro-inflammatory, classically activated macrophages have been shown to be more adherent than alternatively activated macrophages in a variety of assays (Gordon, 2003; Vereyken et al., 2011).
Although classically characterized as directors of cellular migration, chemokines have since have been shown to be involved in a broad range of cellular processes [15], [16], [19].
