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In human, small numbers of T cells producing both IL-17 and IFNγ have been characterized in peripheral blood, in lamina propria of patients with Crohn's disease as well as in patients with psoriasis [ 28- 30], but currently is it not known how such cells are derived from the naïve precursor cells.
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The expression of HDJ2 was characterized in peripheral blood (PB) mononuclear cells (MNC) from HD; PBMNC from RA patients; and MNC from synovial fluid (SFMNC) and ST from RA patients.
While the effect of hyperglycemia has been well characterized in peripheral neurons, we know little about the effect of hyperglycemia on the central nervous system (CNS) partly due to the limitation of noninvasive dynamic imaging techniques to assess neuronal function [2].
Idiopathic hypereosinophilic syndrome (HES) is characterized by peripheral eosinophilia and multiorgan dysfunction in the absence of known causes of hypereosinophilia.
In particular, typical granulomas are characterized by peripheral fibrosis and several layers of epithelioid cells surrounding necrotic areas containing a large amount of acid-fast bacilli [ 33, 48].
First described in 1998, lipodystrophy syndrome is characterized by peripheral lipoatrophy, central lipohypertrophy and other signs and symptoms (Silvers et al 2006).
Sepsis and its common complication septic shock, are generally induced by the action of lipopolysaccharide (LPS) and is characterized by peripheral arteriolar vasodilatation which results in hypotension and inadequate tissue perfusion.
One variant is a late-onset form that affects adults and is referred to as adrenomyeloneuropathy (AMN), which is characterized by peripheral neuropathy and distal axonopathy in corticospinal tracts of spinal cords undergoing spastic paraparesis as a major symptom without brain inflammatory demyelination.
Peripheral multifocal choroiditis occurs mainly in women 55 years of age and is characterized by peripheral punched-out lesions associated with intraocular inflammation.
Sepsis is characterized by increased peripheral protein breakdown, notably in skeletal muscle [ 5, 6], and hepatic synthesis of acute-phase reactants; the ensuing alterations in plasma amino acids may play a key role in SAE.
This condition is characterized by a peripheral endothelial opacity and stromal edema, initially located in the lower quadrants, which may progress in a circumferential pattern.
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