Sentence examples for been characterized as important from inspiring English sources
Mcl-1 s has previously been characterized as important regulators of survival in MM and interesting therapeutic targets [ 44, 45].
These protein sectors have been characterized as important to the protein by either contributing to its biological identity or its function [ 5, 9].
It is interesting to note that two SP1-binding sites have been characterized as important MUC1 transcriptional activators in epithelial cells [ 19, 20].
Microdeletions on chromosome 17q12 encompassing the hepatocyte nuclear factor 1β (haveβ) have recently been characterized as an important cause of prenatally hyperechogenic kidneys, renal aplasia and renal hypodysplasia, which represent an important cause of chronic renal failure among children [ 1, 2].
Recently, survivin has been characterized as an important member of the inhibitor of apoptosis family, with a very complex biology that has not been fully understood yet [8].
Oxidative stress may represent the physiological link between micronutrient supply and chilling tolerance, and has been characterized as an important stress factor in cold-stressed plants [28].
Slit3 has been characterized as an important player in the genesis of the diaphragm and kidney.
The cyclic dinucleotide 3', 5' cyclic guanylic acid (c-di-GMP) has been characterized as an important second messenger that affects a range of physiological traits in bacterial species.
As an efflux transporter for xenobiotics and unwanted toxic compounds, BCRP has been characterized as an important part of self-defense systems in organisms.
The proinflammatory cytokine IL-18 has already been characterized as an important regulator of the innate and acquired immune responses [ 41].
The S. cerevisiae homolog of pzl-1, PPZ1, has been characterized as an important (negative) regulator of salt stress, halo tolerance, and pH homeostasis (Posas et al. 1995; Yenush et al. 2002).
