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His tenure has been challenging, with profits last year falling 13.4% to £123m.
He said: "It's undoubtedly been a good year but it's also been challenging with extreme volatility in the currency and fuel markets.
Tallying the dead at the hands of organized criminal groups has also been challenging, with inconsistent criteria to determine whether a homicide is related to the fight against and among organized crime and drug gangs.
"Weather conditions have been challenging, with snow drifts of up to 15 feet and high winds".
"The last four years have been challenging, with staff reductions, pay restraint and pension changes but I believe the Civil Service has delivered brilliantly on a massive programme of change for the government".
Since the discovery of Warfarin in the 1940s, the design of new warfarin-derived anticoagulants for rodent management has been challenging, with mainly structural modifications performed on the C3 position of the coumarin skeleton.
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"We've been challenged with trying to fill positions.
Exceptions involve a few patients who have been challenged with DF during their individual diagnosis procedure.
Recently, these scenarios have been challenged with genetic as well as fossil data.
Implementation will be challenging with no guarantee of success.
"Those who would criticize Turkey for its problems confuse what is challenging with what is fundamental.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com