Sentence examples for been challenged based on from inspiring English sources
The concept of M type-specific protective immune responses has recently been challenged based on the observation that multivalent M protein vaccines elicited cross-reactive bactericidal antibodies against a number of non-vaccine M types of GAS.
Recently, the wisdom of this approach has been challenged based on the ability of a Gram-positive bacterium to incorporate extracellular fatty acids and thus circumvent the inhibition of de novo fatty acid synthesis.
Indeed, the role of DNA damage as a cause of aging has been challenged based on evidence supporting the idea that aging is a systemic process [ 30].
Nevertheless, the relationship of mitochondria to Rickettsiales has been challenged based on phylogenomic studies that have demonstrated a close relationship of mitochondria to Rhodospirillum rubrum [ 4].
However, this view has been challenged based on a wealth of structural and functional analyses that support a model that the individual respiratory chain complexes interact to form stable supercomplexes (Genova and Lenaz, 2014; Schägger and Pfeiffer, 2000).
Prosecutors considered indicting the city, with the Fire and Buildings Departments coming under intense scrutiny, but chose not to do so, citing concerns that the charges could be challenged based on sovereign immunity.
In fact, if the colonies had been located close to other bee attractive agricultural crops (as may occur in beekeeping) the results could be challenged based on dilution of residues.
The historical approach of the one-hit theory for DNA-reactive chemicals and the view of genotoxicity as an inherent property of a chemical are being challenged, based on a better understanding of the complexity of molecular mechanisms of mutation.
Read coverage was computed and genome annotation was challenged based on read distribution and coverage.
Parental participation is often advocated as important for school-based interventions, however, getting parents involved in school-based interventions appears to be challenging based on earlier intervention experiences.
