To construct Figure 2 and Figure S1, for each method, the total logodds prediction for each probe sequence was calculated (that is, the logodds at each site was summed over all possible sites, with the better of two "orientations" chosen at each site): this was done in order to treat equally the cases of a factor having a few highly specific sites, or several weaker sites.
A single score is calculated that can be compared at different points in time and includes weighting for detrimental effects of the medication [ 82].
For each separate (auto antibody, the consecutive median concentrations from 6 months to 24 months (thus excluding baseline values) were used to produce a linear fit curve, from which the lifetime was calculated (that is, the time point at which the fit curve crossed the x-axis).
Assuming further a molecular weight of 48 kDa for BSF, it can be calculated that at 0.7 mM of calcium and phosphate ions, the optimal turbidity produced by 21 µg/ml, or 0.44 µM, corresponds to the binding of 58 apatite units by each BSF molecule.
It can be calculated that at physiological pH, 7.4, 99.97% of lactic acid is dissociated, and at pH 6 the percentage is still 99.3.
Excluding these imported dogs, it was calculated that at least 0.027% of the 58,000 dogs yearly taken to Southern Europe during holidays become infected with Leishmania.
On the basis of the assumption that all released hypochlorite reacted with APF, it can be calculated that at least ∼4 μM hypochlorite/mM chlorite escaped from the reaction sphere at pH 7.0.
Based on the amount of water lost at 30 min, it can be calculated that at 15 s, the leaves have lost ∼0.01% of the total weight of the leaf, which we consider insignificant.
It was calculated that at least 40 evaluable patients would be required to give a 90% chance of detecting an increase in the rate of grade 3/4 mucositis from 5 to 15%.
Based on an electroactive coverage of 0.17 pmol cm−2 for MtrC, it can be calculated that, at 0.2 W cm−2 light intensity, 30 electrons per second are transferred through each electroactive MtrC.
