Sentence examples for been attributed to defective from inspiring English sources

These catastrophic abnormalities in embryogenesis have been attributed to defective Hh signalling: cilia-derived defects in other pathways simply do not get the opportunity to manifest.

In S. cerevisiae and S. pombe, the defect has been attributed to defective expression and trafficking of the Can1 and Cat1 basic amino acid transporters (Aspuria & Tamanoi, 2008; Urano et al, 2000).

The iron deficit in EPP patients has been attributed to defective iron absorption (Holme et al, 2007a).

A number of different types of cancer have been attributed to defective DNA repair including xeroderma pigmentosum[ 20], hereditary nonpolyposis colorectal cancer[ 21], and breast cancer due to mutations in BRCA1 and BRCA2 as well as other DNA repair genes (e.g., ATM, TP53 and CHK2)[ 22].

Thomsom et al. showed that mature miRNA levels are generally lower in several human primary cancers, despite unchanged pri-miRNA levels and this has been attributed to defective processing by DROSHA[ 45], while DROSHA and DICER have also been shown to be downregulated in endometrial cancer and specific subgroups of breast cancer [ 46, 47].

We examined whether this defect could be attributed to defective expression of Notch on T-PDK1−/− DNs.

We found that Gas1 mutant GI tract has circular smooth muscle defects that can be attributed to defective Hh signaling.

Thus the notion of an organic whole in the above sense must be attributed to defective analysis, and cannot be used to explain things.

Moreover, "gender bias," with a higher prevalence of MS in females could be attributed to defective regulation of X chromosome through epigenetic effects, or to the parent-of-origin effect, where descendants of diseased mothers have greater chance of developing MS than offspring of diseased fathers, caused probably by epigenetic mechanisms such as genome imprinting [13].

Moreover, p110δD910A mice were resistant to infection by Leishmania major and this was attributed to defective Treg expansion and recruitment to the site of infection [20].

Depletion of β-Arrestin 1 was reported to cause CXCR4 trapping in early endosomes, which was attributed to defective recruitment of the ubiquitin ligase AIP4 (atrophinteractingting protein 4 [39]].