Inter-relationships between calcium, mitochondria, and aging have been attributed to accumulated damage from reactive oxygen due to calcium overload of mitochondria [36].
The decline in risk of respiratory syncytial virus-associated LRTI with increasing age has conventionally been attributed to accumulated immunity following previous respiratory syncytial virus exposure, ontogeny of the immune system, and physiological changes, such as larger airways.
Morphological differences may be a response to environmental factors but also they can be attributed to accumulated genetic differences due to disruption of gene flow among populations.
A positive association between parity and periodontal disease might be attributed to accumulated tissue destruction across time rather than an intrinsic parity- related abnormality.
This change can be attributed to accumulating data on organisation in experimental and natural communities, and new perspectives gained from the fields of evolutionary population ecology and phylogenetics ([ 2] e.g., [ 3, 4]).
Other studies, however, report that the likelihood of properly timed vaccination increases with maternal age, which has been attributed to experience accumulated over time on the importance of vaccination and also on fatalities that might have occurred to children who were not vaccinated [ 37, 39, 40].
The decrease in hydrolysis rate over time has been attributed to inhibition by the accumulated end products [ 34].
Historically, the relationship between ageing and carcinogenesis has been attributed to somatic mutations that accumulate in the epithelium over time due to oxidative damage to DNA nucleotide structure and due to failures of DNA damage repair systems.
Traditionally, phenotypic discordances between MZ twin pairs have been attributed to environmental factors; however, accumulating experimental evidence also suggests a role for genetic and, more importantly, epigenetic differences between co-twins.
For example, tsunami earthquakes usually have slow rupture velocities due to rupture complexity and/or low rigidity material, whereas some onshore crustal earthquakes can have very fast supershear speeds that might be attributed to the accumulated stress and smoothness of the fault planes.
