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Since plasma does not produce sufficiently energetic particles or photons to penetrate cells, it had been assumed that cellular genetic material would not be affected; however, formation of intracellular ROS is the major mechanism by which ionizing radiation produces DNA damage [29].
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It is assumed that cellular radiosensitivity is not modified by the space environment, but repopulation rates of stem and stromal cells are reduced as a function of time in weightlessness.
Most, if not all, eukaryotic cells are sensitive to mechanical signals, and it has generally been assumed that the magnitude of the cellular response will correspond to the magnitude of the deformation.
It is assumed that the cellular activity is further activated when the field is turned on (during incubation of PEG-SPION with A549, MDA-MB-231 and Jurkat cells), enabling the SPION to affect the cell metabolism.
Since bystander lymphocytes of the stroma were EBNA-1–, it could be assumed that the cellular source of the PCR EBV signal was the epithelial tumor cells.
Since it can be assumed that the cellular binding affinity for curcuminoids per se remains constant, the variations in the apparent binding KDs may be interpreted as differences in affinities between curcuminoids and solubilization vehicles.
Studies of micro-organisms from which it is assumed that multi-cellular organisms evolved demonstrate the ability of cells subject to environmental stress to adapt to previously un-encountered conditions.
Moreover, due to the shrinkage of dead cells, it can be assumed that the higher cellular density corresponded to a higher concentration of DNA content.
It will, however, not be assumed that the successive cellular changes leading to the development of cancer are necessarily mutations (as was postulated by Nordling (1953)), since there is evidence that carcinogenic and mutagenic activity are not always identical (Berenblum and Shubik, 1949) and since the nature of the cellular change is irrelevant to the mathematical analysis.
For the HM, it was assumed that 80% of the cellular mass of the liver are hepatocytes [ 57].
Previously, it was assumed that mitotic partitioning of cellular material was equal between daughter cells [ 1], however more recent studies have shown that certain cell components partition asymmetrically at mitosis [ 2- 5] and there is a growing realisation that division asymmetry is a fundamental property of biological cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com