Sentence examples for been associated with variants from inspiring English sources

Clopidogrel response has similarly been associated with variants of CYP2C19 (Shuldiner et al., 2009).

For example, a number of autoimmune diseases have been associated with variants in the PTPN22, TNFAIP3 and CTLA4 genes.

Immune-mediated diseases are thought to develop through a complex combination of genetic and environmental factors and have been associated with variants of MHC class I or II genes, which in the dog are referred to as the dog leukocyte antigen (DLA) system.

To use case parent triad data to investigate if cerebral palsy (CP) is associated with variants of the APOE gene, the rs59007384 SNP of the TOMM40 gene or combined haplotypes of the two genes.

VEGFR3 mutations which perturb tyrosine kinase activity are associated with variants of hereditary lymphoedema, reinforcing the pivotal role of VEGFR3 in lymphatic endothelial cell function [ 73].

There are many different types of information that could be associated with variants, from measures of sequence conservation [ 3] to predictions about the effect of a variant on protein structure and function [ 4- 6].

Other AIDs that are associated with variants of IL-23R (that is, psoriasis and AS) are therefore candidates for the assessment of treatments that target the IL-23 pathway.

Generally, immoderate alcohol consumption is associated with variant angina and accepted as one of the risk factors for coronary artery spasm (CAS), but evidence is lacking in this regard.

Specific genes, such as the MYC oncogene, are associated with variant enhancer loci that cluster with other VELs to form super/stretch VELs in many cancer types [ 28].

After applying FPRP and BFDP in women with at least four night shifts, an increased risk of breast cancer was associated with variant alleles of SNPs in the genes AANAT (rs3760138, rs4238989), BMAL1 (rs2278749, rs9694859, rs969485) and ROR-b (rs3750420).

Resting heart rate has been associated with Arg389Gly variants [38], [39].