GDT traditionally has been associated with targeting the DO2I to a supranormal value of >600 ml/minute/m.
Patients with EMD at diagnosis or during disease course were associated with targeted drug resistance.
In the mouse liver, several miRNAs found to be upregulated were associated with targeting mRNAs important for detoxification and regeneration of the liver [11].
Last, the development of postprocedure pneumothorax was associated with targeting smaller lesions (P = 0.03).
Finally, we show that the protective effects of SCs are associated with targeting secondary degeneration, with implications for translating cell-based therapies to the clinic.
D. dadantii also encodes a second locus similar to genes of a T2SS, which is associated with targeting proteins to the outer membrane [ 78].
We show that SC transplantation can be monitored in real time and that the protective effects of SCs are associated with targeting secondary degeneration, with implications for translating cell-based therapies to the clinic.
It has been associated with target selectivity, success in progressing into clinical development and compound safety, among other factors.
Although not extensively studied, 24-h BP variability has been associated with target organ damage among individuals with CKD in at least one study.
A lack of nocturnal BP dipping, or nondipping, has been associated with target organ damage [ 2– 4] and an increased risk of cardiovascular events in individuals with hypertension [ 5– 8], along with cardiac hypertrophy and remodelling in a normotensive population [ 9].
