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Phosphorylation of Hsp25/27 by MK2 has been associated with modification of its oligomerization and regulation of the actin cytoskeleton [9].
In addition, infusion of lipid emulsions in parenteral nutrition has been associated with modification of apolipoprotein C-II [ 6].
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Indeed, chronic, but not acute, leptin treatment modified hypothalamic actin levels, and rearrangement of actin filaments in different brain regions has been associated with modifications in numbers of synaptic contacts and dendritic spines (33– 33).
A multivariate analysis indicated that the major differences in microbial function could be associated with modification of the soil N cycle following agricultural management.
NF-κB activation by API2-MALT1 expressior or upon TNF-α treatment is associated with modification of IKKγ with Lys63-linked polyubiquitin by TRAF6 or TRAF2 respectively [10], [21].
In particular, ribosome alterations are associated with modification of initiation of translation by IRES element and strong defect in translation fidelity.
The VirR and SrtB are associated with modification of the cell surface [45], [46], but the significance of the proteins encoded by these genes in the sakacin P-resistant strain remained to be investigated.
We know that inflammation is associated with modification of eicosanoids with increased generation of thromboxane A2 and prostacyclin.
GH47 proteins are associated with modification or degradation of glycoproteins containing α-1,2-linked mannose residues [ 136].
The ingestion of probiotics is associated with modification in physiological homeostasis of the intestinal flora, which is important in preventing disease, especially infections.
Epidemiological studies show that PCBs are associated with modification of both innate and adaptive immunity, including effects on immune cells and signaling molecules, with implications for both immune response and initiation.
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