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Mutations in mitochondrial DNA have been associated with hypersensitivity to aminoglycosides; no studies have been conducted in Mexicans, which are very prone to such alterations because aminoglycosides have been prescribed carelessly for many years, irrespective of the ailment to be treated.
These factors have been associated with hypersensitivity and neuropathic pain symptoms in various experimental models and human pain conditions, and they could perhaps be related to the burning pain symptoms in BMS patient as well [27, 28].
Aspergillus fumigatus is the etiologic agent of allergic bronchopulmonary aspergillosis (ABPA), has been associated with hypersensitivity pneumonitis, and is a primary cause of invasive aspergillosis in immunocompromised individuals [3].
Aureobasidium has been associated with hypersensitivity pneumonitis (Greinert et al. 2000), but its role in the development of allergic rhinitis is unknown.
1 Constituents of the quadrivalent vaccine, such as aluminium salts, 2 3 polysorbate 80, 4 and yeast, 5 have been associated with hypersensitivity reactions.
Although some encouraging results have been reported in humans (Warren et al., 2006), overall this strategy has not been successful in clinical trials (Bielekova et al., 2000; Kappos et al., 2000; Garren et al., 2008; Freedman et al., 2011), and has been associated with hypersensitivity and anaphylactic reactions in some circumstances (Kappos et al., 2000; Smith et al., 2005).
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Symptom hypersensitivity to acid infusion is associated with hypersensitivity of esophageal contractility.
In sarcoglycan mutant mice, regionally increased cardiac NO was associated with hypersensitivity to carbachol and decreased sensitivity to adrenergic stimulation.
Illing et al. show that the anti-convulsive drug carbamazepine, which is associated with hypersensitivity responses in patients with the HLA-B*15:02 allele, also binds to that HLA molecule and alters its set of associated peptides.
Gregory, C. W., Johnson, R. T. Jr., Mohler, J. L., French, F. S. & Wilson, E. M. Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen.
At the cellular level, FA is associated with hypersensitivity to DNA-crosslinking genotoxins.
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