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While improved glycemic control/insulin sensitivity has been associated with augmented cardiac function in pharmacologic studies, studies on dietary intervention are scarce.
Furthermore, subtherapeutic levels of vancomycin has been associated with augmented renal clearance (ARC) [ 10], which is characterised by an enhanced renal elimination of circulating solutes observed in critically ill patients [ 6, 9, 12].
The loss of IGF-II imprinting has been associated with augmented activation of the PI3K-pathway [ 124] and hence the reports of a field epigenetic effect may indicate that this could be a predisposing factor for these cancers.
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These effects were associated with augmented intestinal MPO activity and oxidative damage such as an elevation of MDA production and a depletion of enzymatic and non-enzymatic antioxidants.
There is evidence that Ca2+ desensitisation contributes to septic shock: in a rat model, acute endotoxaemia was associated with augmented MLCP activity and reduced sensitivity to an α1-adrenergic agonist [10].
The enhanced cytotoxicity of ATO + bortezomib was associated with augmented STAT3 inhibition and JNK activation, up-regulation of Bim, p21, p27, p53 as well as down-regulation of Bcl-2.
There is considerable evidence, both in humans and animals that IFN-γ production is necessary for protective immunity against mycobacterial disease [18] [21] and successful chemotherapy of TB is associated with augmented IFN-γ production [22] [24].
Such post-pubertal DA receptor alterations in the NAcc may be associated with augmented locomotor responses to the higher dose of amphetamine that we observed in adult NHL rats.
In summary, our study indicates that activation of HO-1 accelerates wound healing in normoglycemic and diabetic mice, what can be associated with augmented angiogenesis, increased migratory capacities and improved survival of keratinocytes.
Concomitant to deployment of the AMP generating adenylate kinase isoform network, cardiac stem cell differentiation was associated with augmented AMP nucleotide signaling, increased expression of the AMP-sensor AMPKα2, a major cardiac isoform, and nuclear redistribution of the activated and signaling competent p-AMPKα(Thr172).
Increased pro-inflammatory HDL in SLE is associated with augmented atherosclerosis [ 67].
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