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However, these putative immune prognostic markers have not been assessed simultaneously in the same patient cohort (Coca et al, 1997; Pages et al, 2005; Galon et al, 2006; Forssell et al, 2007; Hojo et al, 2007; Laghi et al, 2009; Ogino et al, 2009; Ferdinande et al, 2011; Mlecnik et al, 2011a).
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And while context is allowed to play a more prominent role and more factors are assessed simultaneously in systems approaches, they are typically only internal factors (cell-internal and body-internal), and typically targeted through interventions in specific molecular pathways (corresponding to aspects 1 and 3 above).
Working memory and reference memory can be assessed simultaneously in free-choice mazes.
This would allow different signaling pathways to be assessed simultaneously in live animals.
This is because the expression of many genes representing different pathways can be assessed simultaneously in the same individual [ 6, 7].
Bacterial load and TNF in TLR2-/-, CD14-/ and TLR2-/-/CD14-/ mice was assessed simultaneously in all knockout mice after infection and values in knockout strains were compared to those in wt mice.
Hence both the latent-to-latent effects (as in Figure 2) and the single/multiple indicator options (as in Figure 3) must be assessed simultaneously in deciding which meaning of a latent (like η3) is appropriate for inclusion in the model.
Thus, respiration and activity as well as body surface temperatures were assessed simultaneously via flow-through respirometry and infrared thermography as described in Section 2.2.
KPS, TKPS and AKPS were assessed simultaneously 1600 times in a total of 306 patients.
Furthermore, AID technology facilitated concurrent generation and phenotyping of transgenic lines, allowing multiple lines to be assessed simultaneously with significant reductions in animal use.
Leukocyte dynamics and microvascular permeability were assessed simultaneously by fluorescence intravital microscopy in the cremaster muscle 15 to 20 hours after induction of sepsis by cecal ligation and puncture in C57Bl/6 mice.
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