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The cytotoxic effect of EGCG has in part been ascribed to cell cycle arrest [ 4, 9].
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Both EMT and high CD44 expression have been ascribed to cells with tumour-initiating properties, so-called cancer stem cells, in breast cancer and other carcinomas [ 8, 12].
This result suggests that troglitazone at low concentrations inhibits telomerase activity independently from cell differentiation, and is an effect that cannot be ascribed to cell toxicity or apoptosis.
In all cell types studied, PI positive necrotic cells (Q2, supplements, Fig. 2S) constituted only a minor population of less than 5%, whereas cells in Annexin positive cells (Q4, supplements, Fig. 2S) have to be ascribed to cells exposing PS.
In the mouse, Breg function has been ascribed to different cell types including B1 cells [ 20], marginal zone B cells [ 21], B10 cells with a CD1dhiCD5+ phenotype [ 22] and transitional cells [ 23].
Two microarray platforms, an in-house printed microarray (14,000 genes) and the Affymetrix U133A array (22,000 genes) were used to probe the molecular effects of selenium dose and form and several selenium-responsive genes were identified, many of which have been ascribed to cancer cell growth and progression.
It has more recently been ascribed to stem cell aging and loss in self-renewing properties [ 75, 78].
Although a specific function has not been ascribed to the basal cell layer, there are widespread gap junctions between the basal cells and the basal cells and intermediate cells.
The abnormal phenotypes of tumor vascular endothelial cells had been ascribed to the tumor cells that aligned on the defective walls of tumor vessels [47], or to the tumor environments which caused abnormal differentiation of normal endothelial progenitors [48].
PODXL inhibits cell-cell interaction through charge-repulsive effects and in normal tissues, its presence has classically been ascribed to hematopoetic progenitor cells [ 4], vascular endothelial cells [ 5] and renal glomerular podocytes where it plays a vital part in maintaining filtration pathways [ 6].
Instead, multiple similar mechanism have been ascribed to virtually every cell type.
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