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Nano-sized hydroxyapatite (HAP) is a well-known biomaterial which has been applied in bone regeneration due to its osteoconductivity.
MSC therapy has been applied in bone and cartilage repair and in the treatment of osteoarthritis [ 3].
Although PHD inhibitors have been applied in bone repair and regeneration, the PHD inhibitors used are mostly nonspecific.
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It is applied in bone filling, protein absorption, and nanobiocomposites [7 10].
The microspheres are hopeful to be applied in bone tissue engineering.
Therefore, these nanocomposite scaffolds have a potential to be applied in bone engineering.
These novel bionanocomposites have unique bioactivity that can be applied in bone implants as scaffolds and tissue engineering in future.
The results indicate that the developed CHT/BG-NPs nanocomposite scaffolds have potential for being applied in bone tissue engineering.
The porous dual α/β-TCP bioceramics with controllable degradation behavior hold great potential to be applied in bone tissue engineering as bone substitutes.
Degradation and bioactivity tests of the ceramic material have been performed showing an enhanced bioactivity and a suitable degradation rate to be applied in bone tissue engineering.
Hydroxyapatite (HA) and Halloysite nanotubes (HNTs) percentages have been optimized in Polycaprolactone (PCL) polymeric matrices to improve mechanical, thermal and biological properties of the composites, thus, to be applied in bone tissue engineering or as fixation plates.
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