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To give a rough idea of the disparity between characterized and uncharacterized sequences, there are ~15 million protein sequences in the UniProt database that are candidates for annotation, while, as previously noted, only 81 000 (0.3%) have been annotated with a GO term based on experimental evidence.
Although pathways are not specifically included in original GENIA annotations, we have noted that many of pathway mentions have been annotated with a generic label (G other_name).
That syntax has then been annotated with a number of other properties, both to the individual atoms and to the molecule as a whole, the latter including both SMILES and InChI strings.
We considered a given gene g and its three NFPs (assuming that all of them have been annotated with a GO term or pathway assignment) to be functionally coordinated when at least 3 of them could be placed into common GO categories or pathways.
Such PPI events have been annotated with a link to the corresponding references.
These 71 were chosen only for the reason that they have been annotated with a gene symbol.
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Scanned hand-written documents which have been annotated with an electronic version of the document's text would also be considered an annotated patient record.
Of these 900 proteins, 664 could already be annotated with a GO biological process term using annotation from GOA (Camon et al., 2004) and allowing all evidence types.
All metabolites were annotated with a metabolite name.
Any process action can be annotated with a precondition.
Proteins are annotated with a detailed description of protein families, biological process and related diseases.
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