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We identified the expression profiles of key developmental genes among the ones that had been annotated, in silico, during pea aphid genome analysis [ 23, 55].
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The lists of genes identified as differentially expressed during microsclerotia development were functionally annotated in-silico to identify genes encoding the different types of proteins that are potentially involved in microsclerotia biogenesis.
Relevant information was annotated in the MINT database.
Videos will be annotated in order to derive the information.
Four peroxiredoxins were annotated in B. pumilus.
Models are annotated in Supplementary Data.
Although 387 nt coding for an intact N-terminal portion of the protein is detected, ftsN has been annotated as a pseudogene because an in silico translation of an adjacent 382 nt reveals a region coding for the peptidoglycan-binding SPOR domain found within the C-terminal portion of FtsN that is peppered with stop codons and frameshifts.
In addition to the differential analysis across the whole transcriptome, we isolated, in silico, the normalized read counts of two subsets of transcripts: those that had been annotated as either ion channels or steroid-related.
For example, if only one of the isoenzymes corresponding to a reaction is annotated, the corresponding in silico knock-out will result in a false negative prediction.
75 transcripts were considered to be dependent on PAR-1 activation and further annotated in silico by Ingenuity Pathways Analysis (IPA) and gene ontology (GO).
An operon consisting of three open reading frames, annotated in silico as methylmalonyl-CoA (mm-CoA) epimerase, mm-CoA mutase (MCM), and meaB, was identified in the sequencing project of the myxobacterium Sorangium cellulosum So ce56.
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