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The role of a few of the MMPs has been analyzed in experimental arthritis models using deficient mice, and the results were variable depending on the MMP analyzed.
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Gene copy-number changes were analyzed in experimental lines of C. elegans which had been subjected to (i) fitness decline via mutation accumulation, and (ii) subsequent adaptive fitness recovery during population expansion for >200 generations.
Of note these samples have been analyzed in different experimental sections together with samples that behaved as the majority of macrophages.
However, we want to note that this comparative analysis of targets in flies and human is hampered by the fact that PUM targets have been analyzed in different experimental set-ups (whole flies versus cultured cells) and therefore, the data is not directly comparable.
The effects of TEA have been analyzed in different experimental models.
In the same vein, lysosomal organelles have been analyzed in different experimental settings, precisely devoted to the understanding of how certain lysosomal cysteinyl proteases, e.g. cathepsins, can contribute to the cross talk between endolysosomes and mitochondria during apoptosis.
The role of non-radiative channels on temperature dependence of the QD recombination efficiency has been analyzed in many details and with different experimental techniques[5 8].
The influence of wear on hole quality has been analyzed in the literature using mainly an experimental approach.
These structures have been analyzed in details combining different theoretical and experimental approaches: X-ray single-crystal diffraction data were used to simulate the molecule-graphite interaction, first using molecular dynamics and then refining the results using density functional theory (DFT); finally, data obtained with DFT were used to rationalize atomic force microscopy (AFM) results.
The effects of these fields on pineal activity have been analyzed in epidemiological studies [ 26– 41] and experimental investigations carried out using different in vivo [ 42– 94] and in vitro models [ 95– 100].
The assays were carried out at least two times for individual experimental conditions, and 30 60 cells were analyzed in each experimental condition in a single assay.
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