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Though Palestinians did not say so publicly, the uprising's raw power has been an open challenge to the established leadership, one capitalized on not only by Islamic ideologues but by grass-roots fighters.
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The Sikh movement was an open challenge to Mughal royalty.
That was an open challenge to the government.
As noted in Section 1.1, characterizing what the ethical supervenes on is an open challenge.
Detecting and visualizing what are the most relevant changes in an evolving network is an open challenge in several domains.
It is an open challenge to implement support for the standardized pipeline descriptions on execution environments such as Spark.
Despite the deluge of genome or proteome data accessible today, the extraction of biologically relevant information is an open challenge.
Still, the early diagnosis, prognosis, and treatment of cancer are an open challenge for the research community.
Because the competition is an open challenge, teams are expected to come up with criteria on which they will ultimately be judged in 2020.
Usually CTTH disability is not severe; however, it is an open challenge in the field of headache management: other than amitriptyline, there are very few effective prophylactic treatments.
The effective timing of policy actions is an open challenge issue to researchers and also a much needed rule of thumb to policy makers and private agents.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com