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In an evolutionary context, rodent florivory may have been an important selective force that caused certain Proteaceae species to shift to rodent pollination.
The complexity of the modern cellular metabolism might have been an important selective pressure in this evolutionary process.
We suggest that the complexity of the modern cellular metabolism might have been an important selective pressure in this evolutionary process.
As a parallel example, our previous computer simulation studies concerning the origin of the RNA world demonstrated that the limitation of replication resources should have been an important selective pressure for the evolution in the RNA world [ 46- 48].
Although the authors attributed the selection for more invasive and aggressive phenotypes to lower resource availability, the spatial distribution of resources could have also been an important selective force driving invasiveness.
The role in host defense makes the evolutionary history of this CNV particularly interesting, because morbidity due to infectious disease is likely to have been an important selective force in human evolution, and to have varied between geographical locations.
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Still, it shows that parasites may be an important selective force in this population of blue tits, selecting for improved parasite resistance.
The relevance of molecular diseases related to misfolding and aggregation [ 43], the importance for cell physiology and evolution of molecular chaperones preventing misfolding [ 44- 46], and comparative analysis of thermodynamic properties of homologous proteins [ 39] all indicate that selection for stability against misfolding is an important selective force.
Predation is an important selective force in evolution [1] [7] and is generally assumed to select against substandard individuals, i.e. the young, senescent, sick, or individuals in poor physical condition [8] [9].
Competition between spermatozoa from rival males for success in fertilization (i.e., sperm competition) is an important selective force driving the evolution of male reproductive traits and promoting positive selection in genes related to reproductive function.
Thus, we consider that the rate of production of ATP and NADPH during light-dependent reactions of photosynthesis was an important selective element that favored the assembly of energy-demanding and redox-regulated AAB routes during the evolution of the plastid.
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