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In agreement, metabolic pathways of progesterone are affected by modifications in the level of gonadal hormones and by pathology or injury with a regional specificity and in a sex-dimorphic way.
This further extends the results of previous studies showing that p53 association with apoptotic target genes is affected by modifications of p53 at Serine 46 [33], [34], [34].
Our data present evidence that the binding affinity of TR for DNA might be affected by modifications that occur in the LBD after ligand binding, without disrupting the oligomerization state of the protein.
Interestingly, the affinity for Hsp70 is affected by modifications of different segments of Sti1.
These include how the enzymatic activity is affected by modifications of the H3 tail, as well as the stabilization of the complex by the AEBP1 cofactor.
These include how the enzymatic activity is affected by modifications of the H3 tail, as well as the stabilization of the complex by AEBP1.
During the past few years, work from different labs have shown how the enzymatic activity of PRC2 is affected by modifications of Histone H3.
Alongside concerns about the social and environmental impacts of the dam, there is interest in monitoring potential changes in the prevalence of vector-borne diseases, which may be affected by modifications to mosquito breeding sites and altered patterns of interaction between people and vectors.
In addition, we show how the transistor behaviour of an amorphous polymer low-voltage transistor is affected by modification of the Al2O3 dielectric with self-assembled monolayers of molecules with different functional groups.
Uptake of azole antifungal drugs is believed to be via passive diffusion through the cell wall and is affected by modification of cell wall structure by altering the glycosylation of surface proteins.
It avoids the unnecessary checking of previously validated parts that have not been affected by recent modifications.
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