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Or yet another, born in a kinder, gentler time, who is giving her husband one of the strange, erotic nightly baths that she's been administering for more than 40 years, baths that have lately, because of a nosy newspaper columnist, become the stuff of legend.
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After first-line failure, second-line chemotherapy was administered for more than half of patients (n = 162).
Antibiotic prophylaxis was administered for more than 24 hours after the operation in 62% of the cases.
Signs of PRIS dependent on duration of infusion occur more frequently with longer propofol infusions irrespective of dose; arrhythmia and other ECG changes belong to this category, occurring more frequently in cases where a whole range of propofol doses were administered for more than 48 hours.
Similar results were found when using R115777; an intermittent schedule at doses of 300 mg or less twice daily produced infrequent toxicity as compared with continuous dosing, and could be administered for more than 6 months using a 21/28 day schedule, provided the twice daily dose did not exceed 240 mg/m2 [ 49].
In fact, trabectedin has been administered for 6 or more cycles in 52% of patients treated with the combination dose and schedule respectively.
For patients with metastatic disease, the definition was more complex; resistance was characterized as: 1) progressive disease (PD) representing the best response to treatment, 2) PD occurring within 4 months after first- or second-line therapy (after an initial clinical benefit), or 3) SD representing the best response if a taxane had been administered for 3 or more months.
7) More than 5bn treatments have been administered for the parasitic infection lymphatic filariasis since 2000.
Intravenous sedation was administered for no more than 40% of the time on mechanical ventilation.
If despite oxygen administration for 30 seconds the HR did not increase, oxygenation was administered for 30 more seconds.
IV EXE infusion was able to prevent the acute adverse effects of PRED on glucose tolerance, and additional benefits from EXE treatment may be expected when both compounds are administered for a more prolonged time period.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com