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The reported increase of circulating adhesion molecules in patients with OSA remains controversial because confounders such as cardiovascular risk factors and left ventricular function have not been adequately controlled for.
Any major change to the significance of predictor would suggest that a factor had not been adequately controlled for and could bias the results.
Furthermore, practice activity and referral patterns have not been monitored concurrently and important prognostic factors have not always been adequately controlled for when measuring patient outcomes.
Maternal ethnicity, BMI, and smoking status are known to affect cffDNA levels, but these confounding factors have not been adequately controlled for in earlier studies.
Finally, it may be that the relationship is due to residual confounding from other factors, either measured or unmeasured, which have not been adequately controlled for.
Since we are unable to rule out the existence of information bias in the measurement of these variables, it is impossible to assure that all variables have been adequately controlled for confounding.
Similar(54)
In particular, anesthesia is a highly relevant confounder, which needs to be adequately controlled for in functional connectivity studies.
Thus, our empirical findings provide strong evidence for the existence of at least half of an environmental Kuznets curve for deforestation, which appears to be the most robust factor explaining differences in forest cover across countries once geo-climatic factors are adequately controlled for.
This potential unmeasured confounding could not be adequately controlled for in the current analyses, although health status, physical activity and comorbidities were taken into account.
Individual socioeconomic variables were adequately controlled for.
Many studies were not adjusted for potential confounders, and many confounders cannot be adequately controlled for in vastly different study arms.
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been successfully controlled for
been effectively controlled for
been adequately replaced for
been adequately studied for
been adequately developed for
been adequately validated for
been adequately articulated for
been adequately accounted for
been adequately described for
been adequately compensated for
been adequately performed for
been adequately adjusted for
been adequately assessed for
been adequately searched for
been adequately paid for
been adequately modeled for
been adequately screened for
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com