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SS was created for the early detection of potential bioterrorism agents and communicable diseases, and has been adapted to monitor non-communicable and chronic disease trends (Paterson and Durrheim 2013).
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The described platform can be adapted to monitor the other types of abused drugs by using suitably selected biorecognition elements.
The presented BAN-specific qPCR assay can be applied in animal feeding trials, in order to control the correct inclusion rates of the probiotic to the feed, and it could further be adapted, to monitor the uptake of the probiotic into the gastrointestinal tract of broiler chickens.
In addition, polysomal profiling can be adapted to monitor translation of specific mRNAs [5].
This assay may also be utilized to detect surface antigens in a range of cell types, and thus may be adapted to monitor the B cell-derived antibody repertoire in different disease contexts.
The primer/template and composition of the exogenous DNA precursor pool can be adapted to monitor replication fidelity in cell extracts expressing various error-prone Pols or mutator variants of accurate Pols.
While, we have used the approach described here to obtain relative information on the rate of protein synthesis in animals with impaired mRNA translation, the method can be adapted to monitor other facets of gene expression such as DNA transcription, RNA splicing, mRNA transport and turnover, and protein maturation.
For example, this assay could be adapted to monitor the association of certain proteins with differently modified core histones.
Impedance cardiography (ICG) has been validated to gather ambulatory physiological recordings and was adapted to monitor cardiac function online during exercise.
In the ACP, the TSR was adapted to monitor the safety of patients on HIV treatment by focusing on suspected renal toxicity related to the use of tenofovir.
Thus, our data suggest that the monitoring of the Dnmt1/PCNA interactions is not a method adapted to analyze the degree of methylation of a specific gene but is adapted to monitor the degree of DNA methylation.
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