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In the last decade, level-set methods have been actively developed for applications in image registration, segmentation, tracking, and reconstruction.
Multi-material nanoparticles have also been actively developed for enhanced sensitivity/fluorescence efficiency, multi-spectral responsibility, multi-functionalization and improved biocompatibility.
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Inhibitors of PI3K/Akt signaling are being actively developed for tumor therapy owing to the frequent mutational activation of the PI3K-Akt-mTORC1 pathway in many cancers, including glioblastomas (GBMs).
Numerous promising candidates have been identified during the last few years, and several are currently being actively developed for commercial production.
Also, strongly scattering nanoparticles have been used to enhance contrast in dark-field microscopy and optical coherence tomography [4] while thermal ablation sing strongly absorbing nanoparticles is being actively developed for targeted therapies of various diseases [5, 6].
Novel drug interaction quantification methods are also being actively developed for drug combination research (41, 42).
Novel cancer vaccines are being actively developed for these and other malignancies.
Novel immunotherapies are being actively developed for immunoresponsive tumours, such as RCC and melanoma.
Through collaboration with the Muscular Dystrophy Association Venture Philanthropy, and the National Institutes of Health Therapeutics for Rare and Neglected Disease (TRND) program, VBP15 is being actively developed for DMD as the initial indication.
So, the project's been actively developed and used for a while.
The latter activities are, of course, the domain of engineering, and many important modern subfields of solid mechanics have been actively developed by engineering scientists concerned, for example, with mechanical, structural, materials, civil, or aerospace engineering.
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