Sentence examples for been activated through the from inspiring English sources

These engineered MBP-specific Tregs could suppress MBP-specific T effector cells, and were also able to suppress T cells with other specificities after Tregs had been activated through the TCR.

In order to ensure that the gene expression data in this study were derived from an NK cell population that had been activated through the FcR alone, we utilized an immobilized IgG assay previously established in our laboratory [ 9].

Ishida H, Li K, Yi M, Lemon SM. p21-activated kinase 1 is activated through the mammalian target of rapamycin/p70 S6 kinase pathway and regulates the replication of hepatitis C virus in human hepatoma cells.

RSK2 is one of four RSK serine-threonine kinases that are activated through the mitogen-activated protein kinase (MAPK) signal transduction pathway.

Furthermore, MAPKs can also be activated through the upstream activation of HER2/neu or RAS.

11 The activity of mTOR also is regulated by cellular stress when intracellular adenosine triphosphate (ATP) levels are depleted, the adenosine monophosphate-activated protein kinase is activated through the tumor suppressor LKB1 (serine threonine kinase 11).

The inactive zymogen is cleaved into active PO by a serine protease, which is activated through the sequential cleavage and activation of other serine proteases [ 46].

Hence, in the context of a class C GPCR homodimer, G proteins might be activated through the ligand-bound subunit (cis-activation) and/or through the other subunit (trans-activation).

These two enzymes thus appear to be activated through the comprehensive effects of several activators with low specificities, physiologically, although it is possible that they have unknown activators with higher specificities.

The pathway enrichment among genes is activated through the same edges by introducing the activation model.

Stress- activated ion channels on the cell surface can be activated through the forces transmitted by the integrins to the channel elements, either directly or through the cytoskeleton.