It must be acknowledged that when the drug effect mechanism is understood and well characterized, complex translational models can be adopted to give a robust translational prediction with certain underlying assumptions.
It must be acknowledged that when randomising only 8 units of analysis the potential for residual confounding, even after identifying and adjusting for other associations with the outcome as above, is considerable.
It must be acknowledged that when the SVR did not change to a large extent, the reliability of CIpw was acceptable and in agreement with recent studies conducted in nonsepsis patients [ 13, 15, 19, 37].
It may further be acknowledged that, when assuming a male-to-female route of transmission, the true effect of male treatment on the incidence of BV might at best be evaluated in a study in which male carriers would be treated prophylactically.
By adopting the law, Congress is acknowledging that when children cannot be safe in their homes it falls to the rest of us to protect them, whatever our ideology.
It should be acknowledge that when interpreting the findings of this systematic review one should take under consideration various limitations and shortcomings.
For one thing, he seems to be acknowledging that major informational problems can develop when new products explode in volume.
It must be acknowledged that there are potential complications when interpreting changes in cerebral perfusion in the upright position.
However, it was acknowledged that since observational studies, even when well controlled, may be subject to bias and confounding still not recognised or allowed for and that the true sizes of the effects may differ significantly [ 33].
It is acknowledged that major ethical issues can occur when the health interest of the pregnant woman is in conflict with the health interest of the fetus [ 15].
It has also been acknowledged by WHO that probiotic microorganisms when administered in adequate amounts confer a health benefit to the host [ 7].
