There was a substantial fall by 2006, to a third of the 1994 figures, in deaths from peptic ulcer and adverse events under surgical care.
We have shown that there is a substantial fall in the accrual of patients to trials beginning after the age of 14 for the tumour types analysed.
In the following week, which coincided with school closures for the Christmas holidays, there was a substantial fall in cases in under 18 year olds, but a small rise in incidence in the older age groups.
Here, we have shown that there is a substantial fall in the IRF-1/IRF-2 ratin in tissues from nine different types of human tumors when compared with the corresponding normal tissue.
There is a substantial fall-off in risk of autism for second- and third-degree relatives of autistic probands [ 9], and some predict that alleles of 10 to 100 or more genes, each of small effect, may underlie the autistic phenotype [ 10, 11].
To return to first principles, most onlookers would probably concede that the modern view of being "educated", whatever it is, represents a substantial falling-off from the standards of the later 19th century.
Nearly a third of all British workers are heading for a substantial fall in their living standards when they retire – with the majority being medium to high earners, ministers have warned.
It is frequently associated with a substantial fall of viral load and increase in CD4 count.
The market has been looking frothy for a good while now, and a substantial fall was inevitable at some point.
He added: "Since the FLS was launched it has contributed to a substantial fall in bank funding cost, this has fed through to a significant improvement in household credit conditions.
