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There has been a substantial development of non-invasive risk scores, biomarker panels and radiological modalities to identify at-risk patients with NAFLD without recourse to liver biopsy on a routine basis.
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It is a substantial development as it relates to the state of the tissue taken from the appellant's polo shirt and hitherto had not been disclosed," said the barrister.
Historically, the QIAS was a substantial development in support of the Australian ECEC system; however it did not achieve the necessary depth in determining quality beyond a minimal threshold.
There has been a substantial increase in social development parameters, such as growth in health and education infrastructure, in Delhi since the year 2000.
Concurrent with the increased wildfire activity has been a substantial increase in residential development within the Wildland Urban Interface (WUI) (Theobald and Romme 2007).
Consequently, tyrosine kinases have been a substantial focus for the development of targeted therapeutics.
This phenomenon has been a substantial obstacle to dengue vaccine development because of the implication that cross-reactive immune responses between DEN serotypes play a part in the pathogenesis of severe disease.
The Colorado plan said one of its considerations in dropping the Janus Fund was that the market-timing revelations "are a substantial negative development for the firm and are a possible indication of poor policies". But the Colorado plan hasn't pulled other pension money under Janus' control.
Increased agricultural production for export and trade of agricultural products and inputs was made possible by a substantial development in services.
The report is "a very substantial development -- a significant indictment of the technology," said David L. Faigman, a professor of law at UC Hastings College of the Law in San Francisco.
From a global perspective, right now we are building up a huge problem in the west with our net debt and this is a substantial problem for development.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com