It was found that a relevant increase in local dose around the nanoparticle could be computed, but the relative enhancement was much smaller than that observed in photon irradiation.
On the other hand, an apparently counterintuitive finding was that despite a relevant increase in TV between PS0 and PS15, diaphragmatic excursion remained almost constant.
The median PFS of the bevacizumab 5 mg/kg group in this trial was assumed to be 5.0 months based on previous studies [ 8, 12], and prolongation of the median PFS to 7.0 months in the bevacizumab 10 mg/kg group was considered to be a clinically relevant increase (i.e. risk reduction of 30%).
Such information is crucial to recognize a relevant increase in the rate of CMV disease once changes of the preemptive protocol have been implemented.
Within the limits of a pre-post design, study findings suggest that anthroposophic therapies are not associated with a relevant increase in total health costs.
Within the limits of a pre-post design, our findings suggest that anthroposophic healthcare in Germany is not associated with a relevant increase in total health costs.
They postulated that the disruption of the ALCAM-mediated adhesiveness is a relevant step, which increased the invasiveness of tumour cells.
This last datum can be interpreted as a result of late access of the patient to a hospital, which many authors also consider to be a relevant factor for increased mortality [ 9, 10, 13, 17, 18, 20, 21, 25],[ 34, 36- 38].
At 12 months posttransplant, there was a clinically relevant increase in eGFR in favor of everolimus.
Nevertheless, in the indeterminate result group there was a clinically relevant increase in lung-cancer-specific distress when comparing T0 with T3.
