Sentence examples for becoming refractory from inspiring English sources

They emphasize early identification of lapses as being critical in avoiding behavior becoming refractory to change.

Furthermore, mutations in other DDR genes such as ATM and TP53 result in tumours becoming refractory to Top 2 inhibitors.

This pathogen has evolved over time, being insidious with each outbreak and becoming refractory to treatments [ 4].

A recent study by the IMWG confirmed that patients generally have a poor outcome after becoming refractory to currently available therapies [ 7].

Noninvasively determining receptor status may be critical in detecting new lesions, categorizing tumors, and determining when disease is becoming refractory with current treatment, thus improving disease prognosis.

Thus, in response to chronic malaria exposure, atypical MBCs appear to differentiate from classical MBCs becoming refractory to BCR-mediated activation and potentially interfering with the acquisition of malaria immunity.

Although variants in these regions are becoming less refractory to detection as researchers switch from exome analysis to WGS, they remain difficult to interpret.

Ovarian cancer has a high response rate, but most cancers eventually relapse and metastasize, becoming resistant and refractory to standard chemotherapy.

Avoid becoming embarrassingly stubborn.

Their success in preliminary trials suggests that these unconventional strategies are close to becoming mainstream options for refractory diseases.

Finally, as deposits grow and comorbidities increase, gout becomes even more severe and difficult to treat becoming what is known as "refractory gout".