Sentence examples for becomes very difficult when from inspiring English sources

The task becomes very difficult when the receptor site possesses a region with unusual conformational flexibility.

On the side of computer assistance, the automated generation of such sketches becomes very difficult when it comes to multi-molecular arrangements such as protein-ligand complexes in a drug design context.

The thing is, this becomes very difficult when most Americans get their "news" from pundits who have their own agenda.

Single-particle cryo-EM becomes very difficult when the particle is less than a few hundred kDa in mass.

This step sounds simple but once you start becomes very difficult when you try to include everything.

However, the computations become very difficult when k ≥ 5.

At this point my life as a mother became very difficult when my paychecks were getting levied to an unlivable level for taxes owed on the former restaurant.

However, the current method becomes very difficult to apply when the question to be addressed is to determine the role of a particular gene in relation to multiple genetic backgrounds or genotypes.

In a World Cup where spinners are likely to play such a large role that is crucial, because once a batting side starts to falter it becomes very difficult to regain momentum when the spin bowlers are on.

If one of those had come through, then there's no real reflection on what should have been done or could have been done… When you win most weeks it becomes very difficult to change the team when players are doing what they're asked to do".

"I'm sure they speak about wages and this is when it becomes very difficult for clubs like QPR to keep their best players.