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In general, when the hyperboloid surface represented by the log-likelihood function is highly irregular in shape with densely distributed local extrema, the search by gradient method becomes very difficult or even impossible.
Will either party have a way to get out of the contract if performance becomes very difficult or expensive?
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They might be short of a few of their big names, but if Stephen Kearney's depleted side are allowed to build any momentum from dummy-half, they could become very difficult – or even impossible – to beat.
It would also lead to "congestion and traffic disruption on London's roads and that enforcement against all those committing contraventions will become very difficult or impossible" for TfL or the police to enforce and would divert staff from other activities.
In the Markov model setting, the inclusion of these characteristics would have necessitated a very short cycle length (e.g., 1 week) and the derivation of transition probabilities would have become very difficult or impossible.
It becomes very difficult for an observer, or the market, to get any idea what the issues are.
At its simplest level it refers to a mass of data held digitally that is so huge it becomes very difficult to analyse, search or process.
My advice to aspiring UNICEF applicants –Join UNICEF when you feel ready because once you are in the organisation, and you understand and realise how important the mission of UNICEF is, it becomes very difficult to find motivation or excuses to leave.
But it also becomes very difficult to criticize the labels or negotiate a better deal down the line.
"In pluralistic societies we have, it becomes very difficult to sustain the hatred or the fear of the shopkeeper you see down the street every day or your colleague from two cubicles over, and that dynamic is what is really a source of optimism for me".
Likewise, if Trump loses North Carolina or Pennsylvania or Florida, it also becomes very difficult for him to win.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com