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Without the underpinning of these key advertising categories, maintaining sales becomes significantly more difficult, as today's publishers have found..
Once partners start leaving the firm, it becomes significantly more difficult to collect unpaid bills from clients, and their collateral can become impaired.
Celtic are caught in a Glaswegian catch-22; with no Champions League to dangle as bait, attracting players of sufficient quality becomes significantly more difficult.
However, structural learning becomes significantly more difficult when variables are continuous, as the number and type of possible dependence relations and interactions becomes infinite.
In addition, inhaled air is filtered before it enters the lungs because clearance of harmful agents becomes significantly more difficult when they are deposited into bronchi and alveoli.
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Since Nakamoto's system adjusts the difficulty of mining to keep the rate of production constant, it will become significantly more difficult once the new chips go online.
That may still be the case after Hochul's win Tuesday, but getting to that outcome just became significantly more difficult.
Over the past year, it has become significantly more difficult and even downright dangerous for Russians to organize or participate in any political activity not sanctioned by the authorities.
Of late, that has become significantly more difficult as his candidacy elevates politicians like King, who sometimes seem to have more in common with Trump than the rest of the party.
Although now the developers' job has become significantly more difficult, as they must keep three resolutions in mind if they want their app to be available on the new iPhone, the old iPhone, and the iPad.
Because, as the senators wrote, "We are concerned that if the administration waits until next year to send to Congress a draft implementing bill, passage of the USMCA as negotiated will become significantly more difficult". They were referring, of course, to Democratic control of the House of Representatives.
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CEO of Professional Science Editing for Scientists @ prosciediting.com