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The SOS binding site (mainly on β5-β6 loop) becomes rigid upon SOS binding (ligand induced fit).
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The NH bond results of native and mutant Tyrp1 structure according to the RMSD, RMSF, Rg, and SASA plot results depicted that the mutant (R326H and R356Q) structural conformation became rigid upon mutation which may lead to disturb the functional behaviour of the protein.
Without the chance to grieve, he said, "that's when our thinking becomes rigid and bitter".
The wire stretches, becomes rigid, geometrical — pure plastic — it is the present era.
Their body language becomes rigid, cold and unnatural.
"All your body becomes rigid like a fried chicken paw".
In diabetic subjects the erythrocyte membrane becomes rigid and non-deformable.
Bye-Bye Humans too have become rigid, intractible in our reliance upon outmoded technologies (gasoline-powered cars, coal-burning power plants) which are poisoning our atmosphere.
Upon infection with P. falciparum, erythrocytes become rigid, most likely due to export of parasite-derived proteins and cross-linking with the red blood cell cytoskeleton (Cooke et al., 2001).
Those of us who can live in the light of this star have the ability to stay fixed and steady upon our goals, as long as we do not become rigid and stubbornly fixed on them.
Otherwise you become rigid".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com