Finding rotary beads became progressively difficult for shorter mutants.
Furthermore, as an individual progresses upward, it becomes progressively more difficult to successfully fulfill the needs of each higher level.
6, 21, 22 With repeated courses of chemotherapy, emesis becomes progressively more difficult to control, although adequate control in the first cycle of chemotherapy is more likely to be associated with control of acute CINV in subsequent cycles.
The mathematics of the Bitcoin system were set up so that it becomes progressively more difficult to "mine" Bitcoins over time, and the total number that can ever be mined is limited to around 21m.
That works for a while but becomes progressively more difficult to sustain.
As systems become safer, it becomes progressively more difficult to detect the remaining vulnerabilities.
As discharge concentrations approach 10 zooplankton·m−3, it becomes progressively more difficult to differentiate compliant from noncompliant samples.
The second source of uncertainty, U2, is due to limitations in visual examination of behaviour because, as the duration of the ECoG event to evaluate gets shorter, the behavioural arrest associated with it also gets shorter, blends into the normal behaviour of the animal and becomes progressively more difficult to distinguish by visual examination.
These infections have become progressively more difficult to treat due to development of resistance to beta-lactam antibiotics and the number of infections due to methicillin-resistant S. aureus (MRSA) has increased [1] [8].
Additionally, once the autoimmune process has begun it might become progressively more difficult to alter, as suggested by animal models where antigen-specific therapies used prior to the onset of disease can be far more effective than the same treatments given at the time of disease onset.
