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According to statistical decision and information theory principles for decision making, using the recommended indices for decision making becomes problematic due to the many different opinions regarding TDI-derived parameters [ 87].
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This became problematic due to the lack of available land between Winchester College and St. Catherine's Hill.
However, with the small number of studies comparing retention rates became problematic due to their varied follow-up length and therefore we could not form any definite conclusions.
Such estimation would, however, have been awkward statistically because proper treatment of the binary outcome is most naturally modeled as a binary logistic regression, which in a standard maximum-likelihood estimation would have quickly become problematic due to separation (see, e.g., Gelman and Hill 2007).
Several participants indicated that a high body weight becomes problematic when the child reaches school age, particularly due to the risk of teasing, social exclusion, and bullying.
The interaction between suburban or urban motorists and farm equipment operators becomes problematic particularly for drivers unfamiliar with the challenges of sharing the roadway with farm equipment due to its large size, slow speed, and limited maneuverability.
Few subjects in the study received tidal volumes <6 ml/kg, making it impossible to determine the tidal volume at which trauma due to atelectasis, derecruitment, and repeated opening and closing of lung units becomes problematic.
"It becomes problematic".
But, multiplied across a population, it becomes problematic.
So in the winter, keeping up with rent becomes problematic.
This is where Delonas's sketch becomes problematic.
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CEO of Professional Science Editing for Scientists @ prosciediting.com