As shown in Figure 1D, when SNX17 was knocked-down in the Jag1-expressing 293 T cells, these cells became less efficient to stimulate the luciferase reporter expressed in the Notch-expressing 3T3 cells.
The tendon becomes less efficient at adaptation to load.
However, diffusion becomes less efficient at long-length scales, where directed transport is more efficient to reach a distant target.
It happens as we get older because the body becomes less efficient at turning protein into muscle, which is why older people need to have more protein.
However, skin becomes less efficient at producing vitamin D as you get older, and official advice states that everyone over the age of 65 should take a daily supplement of vitamin D (10 micrograms per day).
In any case, lower average population sizes in parasitic lineages should mimic the effects of relaxed purifying selection, on a genome-wide scale, because selection becomes less efficient at removing slightly deleterious mutations in smaller populations [ 38].
They contend that "where there are different sets of values, however, consensus-based approaches and knowledge sharing are more difficult to sustain" (p. 923) and conclude that the partnership form of governance becomes less efficient relative to public corporations as heterogeneity increases.
This is particularly evident in the femur more than in the tibia: because of the "procurvatum" present in the femoral shape, the nail inserted into the canal is subject to slight deformation, so that the external guide becomes less efficient, forcing the surgeon to operate using an X-ray image intensifier; this is potentially dangerous for him, the patient and for other people involved [22].
The plant itself becomes less efficient, meaning more fuel has to be burned to produce the same amount of electricity.
Because of this, the liver becomes less efficient, and is less able to process fat into energy, meaning more of it will stick around your midsection.
